Iqela le-Gute Bio Lisungula i-Advanced RO Plant, Yandisa i-NMN Applications

I-Gute Bio Group lishishini elinobuchule obuphezulu elineteknoloji ye-enzyme catalytic kwicandelo lebhayoloji yokwenziwa njengeyona nto iphambili kunye nokusetyenziswa kweteknoloji ezahlukeneyo. Le nkampani ikakhulu iphuhlisa i-biotechnology kunye nophuhliso lwemizi-mveliso. Eyona nkampani iphambili iimveliso ziquka i-glutathione (GSH), i-β-nicotinamide single nucleotide (NMN) kunye ne-sodium citicotinamide (CDPC). Phakathi kwazo, i-glutathione kunye ne-β-nicotinamide single nucleotides zibekwe phakathi kwezintathu eziphezulu eTshayina kwisabelo semarike, kwaye iimveliso zazo zithengiswa eYurophu, eMelika, eMzantsi Korea, eIndiya nakwezinye iindawo zehlabathi.

Ngowama-2025, iGut Biotech yathenga isityalo esisebenza ngokuzenzekelayo esisebenza ngombane esinomthamo weetoni ezili-100 ngeyure. Kule nkqubo ye-reverse osmosis, sisebenzisa i-Dow's high-pressure BW30PRO-400 reverse osmosis. inwebu imodeli, kunye neempompo zophawu lweShimge, kunye nazo zonke iivalvu zepayipi ziya kwenziwa ngentsimbi engangcoliswanga coceko. Ngo-Epreli 2025, ukufakelwa kunye nokuqaliswa kwesi sityalo kugqityiwe kwaye sele sisebenza njengesiqhelo.

I-β β-Nicotinamide mononucleotide (NMN) yi-biomolecule ephambili eyenza ngokuyinhloko njenge-precursor ye-NAD + (nicotinamide adenine dinucleotide). I-NAD + yeyona nto ingundoqo ye-coenzyme ye-metabolism yamandla eselula kunye nemisebenzi eyahlukeneyo yomzimba, kodwa ngobudala, inqanaba le-NAD + emzimbeni womntu lehla kakhulu, elinxibelelene ngokusondeleyo nokuguga kunye nezifo ezinxulumene noko. Ke ngoko, i-NMN ithathwa njengenokuba nezicelo kwezi ndawo zilandelayo ngokuncedisa i-NAD+:

1. Ukuchasa ukuguga kunye nokwandisa ubomi obunempilo

Indlela yokusebenza:

I-NMN ikhuthaza ukulungiswa kwe-DNA kunye nokulibazisa ukuguga kweseli ngokunyusa amanqanaba e-NAD + kunye nokusebenza kwe-sirtuins (intsapho ehlala ixesha elide), ngakumbi i-SIRT1 kunye ne-SIRT3.Iphucula umsebenzi we-mitochondrial kunye nokunciphisa uxinzelelo lwe-oxidative kunye nokuvuvukala. ubomi.Izilingo zeklinikhi zomntu ziyaqhubeka, kwaye iziphumo zokuqala zibonisa ukuba kunokuphucula izibonakaliso ezinxulumene nokuguga (umzekelo, ukuvakalelwa kwe-insulin, ukusebenza kwemisipha).

2. Ukungenelela kwisifo se-Metabolic

Ulwalathiso lwesicelo:Isifo seswekile: i-NAD + ibandakanyeka ekulawuleni i-glucose metabolism, kwaye i-NMN inokuphucula ukuxhathisa kwe-insulin kunye nokulawulwa kweshukela egazini.Ukutyeba kakhulu: Ukukhuthaza i-lipolysis kunye nenkcitho yamandla ngokuvula i-AMPK yokubonisa indlela.

3. I-neuroprotection kunye nomsebenzi wokuqonda

Imiphumo enokubakho: I-NAD + ibandakanyeka ekugcineni umsebenzi we-neuronal kunye nokulungiswa kwe-DNA, kwaye i-NMN inokulibazisa ukuqhubela phambili kwezifo ze-neurodeergenerative (ezifana nesifo se-Alzheimer kunye nesifo sika-Parkinson) .Kwizilingo zezilwanyana, i-NMN inokuphucula umonakalo we-nerve kunye nomsebenzi wokuqonda emva kwe-cerebral ischemia.

4. Impilo yeentliziyo

Inkqubo yokuKhusela: Ngokunyusa amanqanaba e-NAD +, umsebenzi we-vascular endothelial uphuculwe kwaye umngcipheko we-atherosclerosis uyancitshiswa.Izifundo zezilwanyana zibonise ukuba i-NMN inokunciphisa ukulimala kwe-cardiac ischemia-reperfusion.

5. Ukusebenza kwezemidlalo kunye nokusebenza kwemisipha

Inkqubela phambili yoPhando:I-NMN inokuphucula ukunyamezela komthambo ngokunyusa amandla e-mitochondrial metabolism (izilingo kwiigundane zibonise ukwanda kwe-30-50% kwikhono lokuzilolonga) .Ukuxhaswa kwe-NMN kubantu abadala kunokulibazisa i-atrophy ye-muscle kunye nokuncipha kwamandla.